Publications
A Novel Flow Tube with Wide Dynamic Range and Low Flow Rate Measurements Applicable for Spirometers and Breath Analysers
Date: October 2025
Chimata, Raghuveer; Bibi, Sara Boscolo; Hosseiniakram, Pedram; Gatty, Hithesh Kumar – GattyInstruments AB
This study presents a low-cost, easy-to-manufacture novel flow tube that accurately measures respiratory airflow across a wide range, including very low flow rates, while meeting ATS/ERS spirometry standards and enabling precise, high-frequency pulmonary diagnostics.
SPIROLUFT: A Next Generation Breath Analyser Utilising Simultaneous Spirometry & Pulse Oximetry
Date: November 2024
Säfström, Felix – Uppsala University, Disciplinary Domain of Science and Technology, Mathematics and Computer Science, Department of Information Technology.
This work presents the design, implementation, and evaluation of Spiroluft, a mobile embedded spirometer that enables remote diagnosis of pulmonary diseases by simultaneously measuring spirometry and pulse oximetry with accuracy largely compliant with Medical Device Regulation standards.
Development of a Breath Monitoring System Using an STM32 Microcontroller and a Bluetooth Device with Connected MEMS-Based Sensors
Date: May 2024
Ravichandran, Vijayakanna – Uppsala University, Science and Technology Disciplinary Domain, Mathematical and Computer Science Section, Department of Information Technology.
This thesis develops and validates a Bluetooth-enabled, MEMS-based handheld spirometer for home lung function monitoring, demonstrating improved data transmission speed, reliable performance metrics, and effective detection of lung inflammation–related diseases.
Developing and Validation of a Safety-Critical Usability Framework for Dual-User Respiratory Health Systems
Date: June 2026
Chang, Ching Ho – Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Social Sciences, Department of Informatics and Media.
Abstract: The translation of breath analysis system from specialized hospitals to primary care and home self-monitoring introduces
a distinct “dual-user” challenge: a single interface must safely and effectively accommodates both expert clinicians and
lay patients. Existing mHealth usability heuristics fail to adequately address the safety-critical demands of this paradign
shift. To bridge this gap, this thesis introduces the Safety-Critical Interaction Dimensions (SCID), an 18-dimensional
heuristic framework grounded in human-computer interaction (HCI), respiratory clinical practice, and medical device
standards. The framework was developed through a rigorous six-phase methodology including regulatory gap analysis,
HCI expert consultation and clinician validation. The framework achieved a 95% item endorsement rate with strong interrater agreement (Gwet’s AC2 = 0.781). The SCID framework was then applied via heuristic evaluation to Spiroluft®, an
advanced portable breath analysis system. Five evaluators identified 79 unique usability issues across 16 of 18 dimensions,
Notably, the highest-severity issues clustered around forced expiratory maneuver, where interface failure directly threatens
measurement validity and patient safety. Ultimately, SCID offers a regulation-compliant, validated framework for ensuring
user safety in digital repiratoy systems, whether deployed by clinicians in primary care or by patients at home.